anaphase-promoting complex [APC, anaphase-promoting complex (APC/C) (cyclosome)]
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Definition
Glossary of The Cell (5th ed.) by Alberts et al. (2008)
- Ubiquitin ligase that catalyzes the ubiquitylation and destruction of securin and M- and S-cyclins, initiating the separation of sister chromatids in the metaphase-to-anaphase transition during mitosis.
Glossary of "Plant Biology (1st ed.)" by Graham et al. (2003)
- A cluster of proteins that induces the breakdown of cohesin proteins, thus facilitating the separation of chromatids during mitosis.
文献（引用）
- Alberts, B., Johnson, A., Lewis, J. Raff, M., Roberts, K. & Walter P. 2008. Molecular Biology of the Cell, 5th ed. -xxxiv + 1616 pp. Garland Science, New York.
- Graham, L. E., Graham, J. M. & Wilcox, L. W. 2003. Plant Biology. -xxxv + 497 pp. Pearson Education, Inc., Upper Saddle River.
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