Anaphase-promoting complex

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APC/Cから転送)
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目次

anaphase-promoting complex [APC, anaphase-promoting complex (APC/C) (cyclosome)]

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Definition

Glossary of The Cell (5th ed.) by Alberts et al. (2008)

  • Ubiquitin ligase that catalyzes the ubiquitylation and destruction of securin and M- and S-cyclins, initiating the separation of sister chromatids in the metaphase-to-anaphase transition during mitosis.

Glossary of "Plant Biology (1st ed.)" by Graham et al. (2003)

  • A cluster of proteins that induces the breakdown of cohesin proteins, thus facilitating the separation of chromatids during mitosis.

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